《米兰app官网版下载官方版》 2018, 30(11): 1157-1164

人类细胞图谱计划面临的挑战

吴家睿

(中国科学院上海米兰app官网版下载官方版研究院生物化学与细胞生物学研究所，上海 200031)

摘　要：摘　要：“人类细胞图谱”(Human Cell Atlas， HCA) 是米兰app官网版下载官方版领域最近兴起的国际大科学计划，其目标是要采用特定的分子标志物来确定人体的所有细胞类型。该计划的实施面临着巨大的挑战：有些挑战是技术性的，也许在未来能够解决；但是，有些挑战是理论性的，反映出研究者的想法与其研究对象的本性之间有着根本的冲突。

Challenges for Human Cell Atlas

WU Jia-Rui

(Institute of Biochemistry and Cell Biology， Shanghai Institutes for Biological Sciences， Chinese Academy of Sciences， Shanghai 200031， China)

Abstract: Abstract: “Human Cell Atlas” (HCA) has been recently initiated as an international grand research project in the area of life science， with the goal to construct a comprehensive catalog of all human cells based on their molecular biomarkers. The HCA project will face grand challenges， among which some are technical and some are theoretical.